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ENTEROSORBENT ENTEROSGEL IN CLINICAL PRACTICE, 2016

T. Miksa

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]ln order to assess the characteristics of the medical device ENTEROSGEL, establish the method of its use and the safety for users, this report was drawn up in the form of a critical evaluation of the relevant
published clinical studies conducted with ENTEROSGEL and with other at least partially comparable
medical devices already placed on the European market.

-Translation from the Czech language-[/su_expand]

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SAFETY DATA SHEET

Bioline Products s.r.o.

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ABOUT EXPERIMENTAL PRECLINICAL SAFETY STUDYING OF THE MEDICINAL FORM OF A PREPARATION «ENTEROSGEL®,PASTE FOR INTAKE (SWEET)» GIVEN «TNK SILMA LTD.» (MOSCOW), 2010

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]THE STUDY DRUG SAFETY OF "ENTEROSGEL®, PASTA FOR INTAKE (SWEET)" ALLOWS TO RECOMMEND ITS SUBMISSION TO THE TO THE MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION AS LOW-TOXICITY DRUG AS THE PROCEDURE FOR EXPANDING INDICATIONS AND CHANGES IN INSTRUCTION FOR USE. [/su_expand]

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COLLECTION OF RESEARCH PAPERS. ENTEROSGEL RESEARCHES, 2015

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Dzyublik I, Shunko Em, Barbova A. Clinical efficacy of Enterosgel in treatment of rotovirus infections in newborns
Gorodetsky, Tebechevsky F Clinical efficacy of Enterosgel in treatment of patients with hepatitis A
Tkachenko E., Avalueva E. The Clinical Efficacy and safety of Enterosgel in the treatment of diarrhoea-dominant irritable bowel syndrome.
Tkachenko E., Avalueva E. The Clinical Efficacy and safety of Enterosgel in the treatment of Helicobacter Pylori – associated chronic gastroduodentis
Astahov V., Gusev V. The Clinical Efficacy and safety of Enterosgel in complex prevention of fetoplacental dysfunction in pregnant women with earlier syphilis
Usenko D., Gorelov A. The Clinical Efficacy of Enterosgel, in treatment of intestinal infections in chidren with atopic dermatitis.
Radchenko V., Seliverstov P. The Clinical Efficacy and safety of Enterosgel in treatment of predialysis Cronic Renal Falure (CRF) patients.
Nakhashova V. The Clinical Efficacy of Enterosgel in treatment of patients with Chronic Pancreatitis
Karlyichuk A., Kulachek F. The Clinical Efficacy of Enterosgel in complex treatment and prophylaxis of post-operative intraperitoneal in complication of acute cholecystitis
Moroz L., Paliy M. Use of enterosorbent Enterosgel in complex therapy of acute viral hepatitis B with concomitant intestinal dysbiosis
Sokolov E., Majev I. Clinical efficacy of Enterosgel in patients with digestive system-relative pathology.
Paliy I., Tchernobroviy V. Clinical efficacy of Enterosgel in complex treatment of intestinal dysbiosis
Yurchenko A., Nikolaev V. Clinical efficacy of Enterosgel in treatment of intoxication and diarrhoea in patients with AIDS during antiretroviral therapy. [/su_expand]

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COLLECTION OF RESEARCH PAPERS. GASTROENTEROLOGY: NEW APPROACHES, 2014

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Paliy I.G., Reznichenko I.G. A Modern View on the Issue of Enterosorption: Choosing the O ptimal Drug
Tkach S.M. Effectiveness of Enterosorbent Enterosgel in Combined Anti-Helicobacter Therapy for Patients with Peptic Ulcer Disease
Osadchaya O.I., Boyarskaya A.M. Clinical Effectiveness of Enterosorption in Reduction of Endogenous Intoxication Syndrome in Patients with Nonspecific Ulcerative Colitis
Osadchaya O.I., Shmatova E.A., Boyarskaya A.M. Role of Detoxification Therapy in Maintaining Toxin-binding Capacity of Peripheral Blood Albumin in Patients with Alcoholic Liver Disease
Zaytseva N.V., Aminova A.I., Akatova A.A., Minchenko Ye. Yu. Peculiarities of Eradication Therapy for Chronic H. pylori-associated Gastroduodenitis in Children Living in Ecologically Unfavorable Conditions
Fedorova O.V., Fedulova E.N., Tutina O.A., Korkotashvili L.V. Endogenous Intoxication in Inflammatory Bowel Disease in Children: Substantiation of Detoxification Therapy Using Enterosorption Method
Boyarskaya A.M., Osadchaya O.I., Zhernov A.A., Kovalenko O.N.Use of Enterosorbent Enterosgel in Combination Treatment of Intestinal Dysbiosis in Children with Burn Disease
Enterosgel® in Gastroenterology: Posology and Method of Administration
Dosage and Administration of Enterosgel® for the Treatment of Acute Diarrhea [/su_expand]

 

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COLLECTION OF RESEARCH PAPERS. ALLERGOLOGY, IMMUNOLOGY, DERMATOLOGY: NEW APPROACHES, 2013

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]J. Bystron: “...the basis of allergy management consists first and foremost of the identification of the causal allergen and the effort aimed at its elimination...”
Nagornaya N.V., Dubovaya A.V. The Detoxifying Potential and Clinical Effectiveness of the Enterosorbent Enterosgel in the Combination Therapy of Various Diseases in Children and Adults
Shamov B.A., Malanicheva T.G. Correction of Systemic Endotoxemia in Children with Atopic Dermatitis
Melnykov O.F., Zabrodska L.V., Tymchenko M.D., Sydorenko T.V., Naumova O.A. A Clinical and Immuno-Allergological Study of the Efficacy of Enterosgel in Food Allergy
Malanicheva T.G., Khaertdinova L.A. Enterosorption in the Treatment of Pediatric Atopic Dermatitis Complicated by Fungal Infection
Baranov A.A, Geppe N.A, Karpushkina A.V. The Efficacy of Enterosgel in the Treatment of Children with Bronchial Asthma and Atopic Dermatitis
J. Bystron. Application of Enterosorption Method with Organosilicon Enterosorbent Enterosgel in the Integrated Treatment of Allergic Diseases
Zaytseva N.V, Aminova A.I., Ustinova O.Yu., Akatova A.A., Luzhetskiy K.P. Asthma Prevention in Children with Recurrent Wheezing Bronchitis Who Have Elevated Levels of Heavy Metals and Aldehydes in the Body
Basieva O.Z., Basiev Z.G. Enterosgel in the Combination Treatment of Atopic Bronchial Asthma
Chorna O.O, Binda T.P. On the Issue of the Treatment of Children with Allergic Diseases
Enterosgel® in Allergology and Dermatology: Posology and Method of Administration [/su_expand]

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ENTEROSGEL, 2010

Nikolaev V.G.

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ROLE OF ENTERAL SORPTION IN THE LIPID-LOWERING THERAPY IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS ACCOMPANIED BY ISCHEMIC HEART DISEASE AND TYPE II DIABETES, 2010

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Dolzhenko M.N., Šipulin V.P., Sokolova L.K.

Conclusions
1. The presence of NASH, which occurs in 62.5% of patients with coronary heart disease and type II diabetes, requires reassessment of complex lipid-lowering therapy used in the studied patient groups due to the frequent concomitant liver pathology.
2. Use of Enterosgel in the complex treatment of NASH patients on the background of CHD and type II DM is an effective and safe method of hyperlipidemia correction.
3. Enterosgel helps to eliminate syndrome of lipid distress (lipid distress syndrome-), including diabetic dislipidemia, reduce the activity of systemic inflammation and atherogenic potential of blood plasma.
4. Enterosgel helps to improve the functional state of the liver.
5. Based on the data obtained, absorbent Enterosgel can be considered as an effective means in preventing the progression of the atherosclerotic process in patients with NASH and concomitant coronary artery disease and type II DM.

Keywords: adsorbent, hyperlipidemia, lipoproteins, non-alcoholic steatohepatitis, coronary artery disease, diabetes mellitus, sorption, cholesterol, Enterosgel. [/su_expand]

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ENTEROSORPTION AS AN IMPORTANT METHOD OF TREATMENT OF ELIMINATING CHRONIC ENDOTOXIN AGGRESSION, 2007

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Chernikhova E.A., Anikhovskaya I.A., Gataullin Yu.K., Zakirova D.Z., Ivanov V.B., Saveliev A.A., Yakovlev M.Yu.

Conclusions
Method of intestinal adsorption (enterosorption) can be used as a means of CEA elimination. Monotherapy with Enterosgel, the intestinal adsorbent of new generation, reduces the average LPS concentration in the general circulation by 56% and is capable to eliminate CEA in every fourth patient with chronic inflammatory diseases. [/su_expand]

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ON ESTABLISHMENT OF LARGE-SCALE PRODUCTION AND HEALTHCARE IMPLEMENTATION OF NOVEL HIGHLY EFFECTIVE POLYORGANOSILOXANE-BASED ADSORBENT DRUGS WITH DETOXIFYING EFFECT, 1994

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Bezlyuda N.P., Baranyuk A.P.

Novel intestinal and topical adsorbent drugs with detoxifying effect (studies were conducted in 1980-1990 by order of Main Military Clinical Hospital of the Ministry of Defense of Ukraine) were widely evaluated in military medical facilities. The Military Hospital of Kyiv (nowadays the Main Military Clinical Hospital of the Ministry of Defense of Ukraine) participated in the medical and biological evaluation of novel drugs from the beginning of their development (V.N. Fadeev, F.G. Novikov, N.P. Bezlyuda). [/su_expand]


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