Gastroenterology

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ENTEROSORPTION AS AN IMPORTANT METHOD OF THE ALLEVIATION OF CHRONIC ENDOTOXIN AGGRESSION, 2007

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Chernikhova EA, Anikhovskaia IA, Gataullin IuK, Zakirova DZ, Ivanov VB, Savel'ev AA, Iakovlev MIu.

The study of 25 patients with chronic inflammatory diseases (HID) in stage of remission has demonstrated efficiency of intestinal absorption method (enterosorption) to reduce significantly the total concentration of bacterial lipopolysaccharide (LPS) in the general circulation.
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EFFICACY OF SORPTION THERAPY IN PATIENTS WITH CICATRICIAL ESOPHAGEAL STENOSIS, 2006

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Yu. V. Chikinev, A.R. Antonov, A.V. Korobeinikov

The treatment of patients with post-burn cicatricial esophageal stenosis is associated with considerable challenges due to inflammation, edema of the prestenotic esophagus as a result of traumatization by probes and prolonged contact with food masses. This aggravates the already slow passage of food and, therefore, worsens the nutritional status of patients. Reduction of inflammation and edema requires the use of medications that contribute to the relief of these pathological changes. The positive effect on the mucous membrane, the anti-edema effect was observed during the use of oral intestinal adsorbents (enterosorbents).
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Effects of Melatonin, Aluminum Oxide, and Polymethylsiloxane Complex on the Expression of LYVE-1 in the Liver of Mice with Obesity and Type 2 Diabetes Mellitus, 2016

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S. V. Michurina, I. Yu. Ishchenko, S. A. Arkhipov, V. V. Klimontov, L. N. Rachkovskaya, V. I. Konenkov, and E. L. Zavyalov

Non-alcoholic fatty liver disease is one of the most common complications of obesity and type 2 diabetes mellitus (DM2). The structural trace of metabolic changes in the liver during the development of obesity and DM2 is largely determined by the status of sinusoidal cells involved in the formation of the blood — lymph barrier, including epithelial, Kupffer, Ito, and Pit cells [1]. Endothelial cells of hepatic sinusoids express the lymphatic vessel endothelial hyaluronan receptor marker LYVE-1 [10]. The expression of LYVE-1 in the liver in DM2 and the relationship between LYVE-1 expression and structural and functional changes in the hepatic vessels are not been studied.
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THE STARTING THERAPY OF COLIBACILLOSIS IN CHILDREN, 2016

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"] A.V. Gorelov, A.V. Bondareva

The colibacillosis are wildly spread all over the world and takes leading positions in etiological structure of acute intestinal infections in children. In our country, due to diagnostic difficulties, rate of registration of colibacillosis is low. The clinical epidemiological characteristics and issues of differentiated diagnostic of the given disease are studied insufficiently. Until nowadays, common approaches to therapy are lacking. The article presents evaluation of therapeutic activity of various methods of start therapy of colibacillosis in children. The clinical efficiency of various classes of antibacterial medications and enterosorbents are presented.
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REMOTE RESULTS OF OBSERAVTION OVER THE PATIENTS WITH RHEUMATOID ARTHRITIS WITH COMORBID INTESTINAL DISBACTERIOSIS, 2016

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Mikulets L.V., Voloshyn О.І., Tovkach Y.V.

Remote results of a comprehensive treatment of patients with rheumatoid arthritis with comorbid intestinal disbacteriosis after additional administration of Quercetin, Bifilact extra and Enterosgel to the standard therapy were analyzed. It was found that after administration of a comprehensive therapy including the above mentioned medicines the course of the disease of patients with RA and their general condition improved, the period or remission became longer, the necessity of repeated admissions to the hospital decreased.
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ROLE OF ENTEROSORPTION IN THE TREATMENT OF LIVER DISEASES, 2008

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]I.G. Paliy, MD, Professor, Department of outpatient therapy and family medicine, National Pirogov Memorial Medical University, Vinnytsya

Thus, the high efficiency of enterosorbent Enterosgel, its selective sorption action, simplicity and safety, and the possibility of a combination with other medications allow the medical officer to optimize the therapeutic tactics in various diseases of the liver, to achieve high efficiency and reduce time of treatment and rehabilitation of patients.
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EFFECTIVENESS OF ENTEROSORPTION METHOD IN GASTROENTEROLOGY, 2008

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"] I. G. Paliy, I. G. Reznichenko

The high effectiveness of intestinal adsorbent (enterosorbent) Enterosgel as a detoxifying agent in infectious and inflammatory diseases is associated with its ability to adsorb MWM and pathogenic micro-organisms, thereby positively influencing the cellular and humoral immunity. Enterosgel contributes to enhancing the functional activity of neutrophilic granulocytes to the level of subcompensation. Enterosorption with Enterosgel contributes to restoring the functional activity of T lymphocytes and B lymphocytes.
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A MODERN VIEW ON THE ISSUE OF ENTEROSORPTION: CHOOSING THE OPTIMAL DRUG, 2008

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]I. G. Paliy, I. G. Reznichenko

Enterosgel also exhibits selectivity towards microorganisms as it actively binds pathogenic and opportunistic microflora though does not inhibit the normal microflora, thus eliminating intestinal dysbiosis.

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CLINICAL EFFECTIVENESS OF ENTEROSORPTION IN REDUCTION OF ENDOGENOUS INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC ULCERATIVE COLITIS, 2009

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]O.Osadchaya, A. Boyarskaya

In patients with active UC there is a significant decompensation of toxin-binding capacity of albumin. Meantime, involvement of globulins occurs in processes of toxins elimination, which alter their properties and can cause development of infectious complications in patients with UC.

Use of enterosorbent Enterosgel in combination treatment of patients with UC helps to reduce toxic load on natural detoxification systems and maintain optimal value of toxin-binding capacity of albumin. Meantime, decreased role of serum globulin fraction in detoxification processes maintains their basic functional capacities, thereby reducing the risk of infectious and autoimmune complications in patients with UC.
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EFFICIENCY AND SAFETY OF SILICEOUS ENTEROSORBENTS IN THE THERAPY OF HELICOBACTER PYLORI-ASSOCIATED DISEASES OF THE UPPER GASTROINTESTINAI TRACT, 2016

[su_expand height="30" link_style="dotted" link_align="left" more_icon="icon: chevron-down" less_icon="icon: chevron-up"]Evgenii I. TKACHENKO, Elena B. AVALUEVA, Ekaterina V. SKAZYVAEVA, Sergey V. IVANOV, Igor V. LAPINSKII, Anna V. PUSHKINA, Olga I. MEDVEDEVA

Clinical trials have demonstrated the safety and efflcacy of Enterosgel administered as a monotherapy to treat patients with H. pylori - associated gastroduodenitis.
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