I.G. Paliy, MD, Professor, Department of outpatient therapy and family medicine, National Pirogov Memorial Medical University, Vinnytsya

Thus, the high efficiency of enterosorbent Enterosgel, its selective sorption action, simplicity and safety, and the possibility of a combination with other medications allow the medical officer to optimize the therapeutic tactics in various diseases of the liver, to achieve high efficiency and reduce time of treatment and rehabilitation of patients.

Koval M.I., Pokotylo O.S.

The results of the influence of enterosorbent “Enterosgel” on the LPO and activities of antioxidant protection enzymes in the one, six-, and twelve-month white rats are given. The study was performed on the model of experimental paracetamol damage of the liver of white rats. It is established that the enterosorbent Enterosgel has antioxidant properties, which were manifested in the decrease of plasma levels of diene conjugate (DC) and malonic dialdehyde (MDA), as well as in the recovery of activities of SOD and catalase in the blood plasma of experimental animals, especially, one- and twelve-month ones.

Key words: paracetamol, hepatitis, rats, lipid peroxidation.