THE MANAGEMENT OF ACUTE GASTROENTERITIS IN CHILDREN, 2012
M. Plescik-Lech, R. Shamir, A. Guarino, H. Szajewska
Efforts to improve the taste and/or efficacy of oral rehydration solution (ORS) continue, and some interventions are promising. While standard (over 24 h) nasogastric rehydration is still being used, new evidence confirms that
rapid (over 4 h) rehydration is also effective. For intravenous rehydration, new evidence is available regarding rapid or ultrarapid and large-volume vs. standard-volume rehydration; as the new evidence is not consistent, until
more data are available, the administration of 20 mL/kg seems appropriate.
Convincing evidence has accumulated showing that ondansetron reduces the risk for vomiting; however, a clearance on safety in children is needed. New evidence has reconfirmed that in Europe, where zinc deficiency is rare, there is no benefit from the use of zinc. New data, although mainly from outside of Europe, have reconfirmed that either smectite or racecadotril is an effective adjunctive therapy to oral rehydration. There is a clear effect of using certain probiotics, such as Lactobacillus GG or S. boulardii.
The performed analysis showed that administration of Enterosgel in treatment of the patients with enteroidea allowed reducing the duration of hospital stay by 2-3 days, which is due to a faster normalization of stool and disappearance of the guiding symptoms. No adverse and hypersensitivity reactions were detected upon its administration.
Thus, the data obtained allows one to consider Enterosgel as a more efficient enterosorbent compared to Smecta.