All Clinical Studies Tagged: non-specific ulcerative colitis
CLINICAL EFFECTIVENESS OF ENTEROSORPTION IN REDUCTION OF ENDOGENOUS INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC ULCERATIVE COLITIS, 2009
O.Osadchaya, A. Boyarskaya
In patients with active UC there is a significant decompensation of toxin-binding capacity of albumin. Meantime, involvement of globulins occurs in processes of toxins elimination, which alter their properties and can cause development of infectious complications in patients with UC.
Use of enterosorbent Enterosgel in combination treatment of patients with UC helps to reduce toxic load on natural detoxification systems and maintain optimal value of toxin-binding capacity of albumin. Meantime, decreased role of serum globulin fraction in detoxification processes maintains their basic functional capacities, thereby reducing the risk of infectious and autoimmune complications in patients with UC.
The present problem’s urgency is known to steam from a practical lacking of any important advances in treatment modalities for as common diseases as pathological conditions of the small intestine with allergic manifestations as well as those due to the gastric and small intestine resections of different length (malabsorption syndrome), colonic pathology with dysbiosis manifestations (irritable bowel syndrome, constipation syndrome). At the same, it should be mentioned that the disponible modalities of selective enterosorption and nutritional correction of impaired homeostasis are not utilized sufficiently enough.