CLINICAL AND EPIDEMIOLOGICAL FEATURES, THERAPY ISSUES OF NOROVIRUS INFECTION IN CHILDREN, 2009
1. The rate of mono and combined norovirus infection is high in the structure of acute intestinal infections in children admitted to the hospital and amounts to 16.8% and 13.1%, respectively. It ranks second in frequency after rotavirus. Most often norovirus infection affects children aged 3-6 years.
2. There is a distinct seasonality of norovirus infection, which coincides with that of rotavirus infection. Frequently noroviruses cause disease in winter and spring months (December, January, March).
3. The clinical picture of norovirus infection is characterized by acute onset, with repeated vomiting, intoxication symptoms, mild catarrhal symptoms, gastrointestinal lesions by gastroenteritis type, and exsicosis, degree I-II. Reliably and quickly clinical symptoms stopped in children older than 3 years of age. The younger the child’s age, the higher severity of clinical symptoms.
4. Norovirus and rotavirus infections have significant differences in clinical manifestations. Rotavirus is marked with wider clinical symptomatology, persisitng for a longer time compared with norovirus infection. In norovirus infection the stool is significantly less watery than in rotavirus infections, while repeated vomiting is observed more frequently.
5. The use of antibiotics in the treatment of norovirus infection in children is inappropriate. The optimal therapy is a combination of oral rehydration and probiotics, reducing the duration of intoxication symptoms and providing more rapid relief of GIT symptoms.