Drug Enterosgel® at a dose of 45 g did not show statistically proven impact on the dynamics of the amount of ethanol vapor in the breath after drinking a strong alcoholic drink (whiskey Jameson 40%) in 100 ml while taking the drug after 60 min and 120 min after drinking alcohol but there was a trend to a more rapid decrease in the concentration of alcohol in the breath while taking the drug Enterosgel® by 3rd hour from the moment of reception of alcohol. Proven effect of the study drug was detected in case of the use of strong alcoholic drink (whiskey Jameson 40%) 200 ml. Subjective sensation of sobering speed did not change in patients receiving the study drug.
Thus, the drug Enterosgel® at a dose of 45 g has an impact on the dynamics of amount of ethanol vapor in expired air after administration of a strong alcoholic drink, which manifests itself as a more pronounced decrease in the amount of ethanol vapor in exhaled air over time. The effect has been identified while taking the drug both after 60 min and 120 min after drinking.
AGE CHANGES OF ANTIOXIDANT-PROOXIDANT BLOOD STATUSES IN RATS DURING PARACETAMOL POISONING AND THEIR CORRECTION WITH ENTEROSGEL, 2008
Koval M.I., Pokotylo O.S.
The results of the influence of enterosorbent “Enterosgel” on the LPO and activities of antioxidant protection enzymes in the one, six-, and twelve-month white rats are given. The study was performed on the model of experimental paracetamol damage of the liver of white rats. It is established that the enterosorbent Enterosgel has antioxidant properties, which were manifested in the decrease of plasma levels of diene conjugate (DC) and malonic dialdehyde (MDA), as well as in the recovery of activities of SOD and catalase in the blood plasma of experimental animals, especially, one- and twelve-month ones.
USE OF ENTEROSGEL IN THE TREATMENT OF ALCOHOL INTOXICATION AND ITS CONSEQUENCES, 1990
Kajdaulova A.B., Vasilenko I.V.
Recently, the most challenging problem of narcology is treatment of alcohol intoxication, removal of drunkenness and reduction of withdrawal syndrome.
The complexity of massive elimination of the consequences of alcohol intoxication and treatment of acute psychosomatic disorders arising from it is a result of highly polymorphic disorders associated with significant changes in homeostasis.
An important factor in worsening of these conditions is disruption of the detoxification function of liver and excretory function of kidneys in people consuming alcohol excessively.
Detoxification herapy is the leader in a group of curative measures aimed at correcting homeostasis disorders and reduction of toxic effects of alcohol.