All Clinical Studies Tagged: drug-induced liver damage
AGE CHANGES OF ANTIOXIDANT-PROOXIDANT BLOOD STATUSES IN RATS DURING PARACETAMOL POISONING AND THEIR CORRECTION WITH ENTEROSGEL, 2008
Koval M.I., Pokotylo O.S.
The results of the influence of enterosorbent “Enterosgel” on the LPO and activities of antioxidant protection enzymes in the one, six-, and twelve-month white rats are given. The study was performed on the model of experimental paracetamol damage of the liver of white rats. It is established that the enterosorbent Enterosgel has antioxidant properties, which were manifested in the decrease of plasma levels of diene conjugate (DC) and malonic dialdehyde (MDA), as well as in the recovery of activities of SOD and catalase in the blood plasma of experimental animals, especially, one- and twelve-month ones.