ON ESTABLISHMENT OF LARGE-SCALE PRODUCTION AND HEALTHCARE IMPLEMENTATION OF NOVEL HIGHLY EFFECTIVE POLYORGANOSILOXANE-BASED ADSORBENT DRUGS WITH DETOXIFYING EFFECT, 1994
Bezlyuda N.P., Baranyuk A.P.
Novel intestinal and topical adsorbent drugs with detoxifying effect (studies were conducted in 1980-1990 by order of Main Military Clinical Hospital of the Ministry of Defense of Ukraine) were widely evaluated in military medical facilities. The Military Hospital of Kyiv (nowadays the Main Military Clinical Hospital of the Ministry of Defense of Ukraine) participated in the medical and biological evaluation of novel drugs from the beginning of their development (V.N. Fadeev, F.G. Novikov, N.P. Bezlyuda).
The performed analysis showed that administration of Enterosgel in treatment of the patients with enteroidea allowed reducing the duration of hospital stay by 2-3 days, which is due to a faster normalization of stool and disappearance of the guiding symptoms. No adverse and hypersensitivity reactions were detected upon its administration.
Thus, the data obtained allows one to consider Enterosgel as a more efficient enterosorbent compared to Smecta.