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ALLERGOLOGY AND DERMATOLOGY
Modern pediatrics 3 (37) / 2011

FORECASTING HEALTH STATUS OF CHILDREN WITH EARLIEST MANIFESTATIONS OF ATOPIC DERMATITIS

T.L. Protsyuk, N.I. Tocarchuk, L.A. Protsyuk, О. V. Chirkа, N.M. Surkovа, L.D. Kotsur
National Pirogov Memorial Medical University,  Vinnytsya Regional Children’s Clinical Hospital

MATERIAL AND METHODS OF THE STUDY
90 infants in the first year of life with severe (45 patients) and moderate (45 patients) atopic dermatitis (group 1) and 50 patients in the first year of life with mild forms of atopic dermatitis – (group 2) were examined. Follow-ups of children were carried out during 4 years.


Summary. The prognosis of early manifestations of atopic dermatitis depends on the quality of supervision, the adequacy of the antiallergic activities and severity of clinical manifestations of the pathological process of the skin. Immune status of children with severe and moderate atopic dermatitis is characterized by decreased levels of total IgG, hyperimmunoglobulinemia E, low IgA in patients over the age of 6 months. In severe and moderate atopic dermatitis a significant delay in timing of vaccination in children is observed. In mild atopic dermatitis most of the children’s vaccination is timely performed. Vaccination of children with early manifestation of moderate to severe atopic dermatitis should be carried out during the period of remission on the background preparation. Preparations for the vaccination can inculcate children with severe atopic dermatitis without any side-effects and pronounced exacerbation of the pathological process.
Key words: atopic dermatitis, children, specific IgE, vaccination.

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